Lyophilizers - Sterilizers - Autoclaves

24 Machines
Freeze dryers, sterilizers, and autoclaves are essential process machines for ensuring the preservation, safety, and compliance with hygiene standards of products and equipment in the pharmaceutical, biological, nutraceutical, and food sectors. Makinate offers a wide selection of used freeze dryers, sterilizers, and autoclaves from leading manufacturers such as De Lama, Fedegari, Getinge, and other specialized brands, providing reliable solutions for laboratories and industrial production.

Freeze dryers for product preservation

Freeze dryers are primarily used in the pharmaceutical, biological, and nutraceutical industries to preserve the quality and properties of sensitive products.... The freeze-drying process involves dehydrating previously frozen products to extend their shelf life while maintaining their organoleptic properties and active ingredients. Freeze dryers are equipped with cooling compressors with refrigerant, which ensure precise temperature control throughout the entire freeze-drying cycle.

Applications of freeze dryers

Freeze dryers are also used in the food industry, where they are employed to produce many commonly used products. Examples of freeze-dried products include instant coffee, instant tea, dried fruits, and vegetables for soup mixes. This technology allows products to be preserved for long periods while maintaining their nutritional and organoleptic qualities.

Sterilizers for container safety

In the pharmaceutical sector, sterilizers are used to sterilize bottles, vials, or ampoules before filling. These machines are essential to ensure that containers intended to hold pharmaceutical, biological, or nutraceutical products are free from microbial contamination, guaranteeing the safety of the final product and compliance with GMP regulations.

Types of sterilization

Sterilizers can be configured for various treatments, including sterilization of solid and porous materials, sterilization of filled vials under rapid vacuum, sterilization with cooling using water spray under sterile air backpressure, tindalization, pasteurization, and inactivation. The flexibility of these systems makes them suitable for a wide range of processes depending on specific production requirements.

Autoclaves for equipment sterilization

An autoclave is a device used to sterilize different types of equipment, from laboratory instruments to surgical tools, by exposing them to high-pressure steam. Autoclaves are essential to ensure the sterility of instruments and equipment that come into contact with pharmaceutical or biological products, effectively eliminating bacteria, viruses, spores, and other microorganisms.

Technical features

All freeze-drying, sterilization machines, and autoclaves are, of course, constructed from 316L stainless steel, a material that ensures corrosion resistance, ease of cleaning, and compliance with hygiene standards required in the pharmaceutical, biological, and food sectors.

Application sectors

Freeze dryers, sterilizers, and autoclaves are used in various industrial and research areas:
  • Pharmaceutical and biological sector: for the preservation of medicines, vaccines, sera, and sensitive biological products
  • Nutraceutical sector: for supplements, probiotics, and products requiring long-term storage
  • Food sector: for coffee, tea, fruits, vegetables, and freeze-dried food products
Investing in used freeze dryers, sterilizers, and autoclaves through Makinate allows pharmaceutical, biological, nutraceutical, and food companies to access advanced process technologies at significantly lower costs compared to purchasing new systems, while maintaining high standards of quality, safety, and regulatory compliance, ensuring safe and effective products and production processes.
fedegari-fod4f-m2508225070

Used Fedegari FOD4/F sterilizer

  • Code: M2508225070
  • Status: Visible
  • Condition: Good
  • Year: 1995
Technical sheet
de-lama-dloav-75-1-m2550372251

Used De Lama DLOAV 75 1 sterilizer

  • Code: M2550372251
  • Status: Visible
  • Condition: Good
  • Year: 2018
Technical sheet
serail-cs15-1-m2525288475

Used SERAIL CS15-1 lyophilizer

  • Code: M2525288475
  • Status: Visible
  • Condition: Good
  • Year: 2009
Technical sheet
fedegari-fof-4-m2537391738

Used Fedegari FOF 4 sterilizer autoclave

  • Code: M2537391738
  • Status: Visible
  • Condition: Good
  • Year: 1991
Technical sheet
fedegari-fof-4-m2515201282

Used Fedegari FOF 4 sterilizer autoclave

  • Code: M2515201282
  • Status: Visible
  • Condition: Good
Technical sheet
matachana-501rc2-m2557255142

Used Matachana 501RC2 autoclave

  • Code: M2557255142
  • Status: Visible
  • Condition: Good
  • Year: 1999
Technical sheet
steriline-st-0-m2482148642

Used Steriline ST 0 sterilizer

  • Code: M2482148642
  • Status: Visible
  • Condition: Good
  • Year: 2009
Technical sheet
mp-20-kg-m2492509594

Used mp 20 kg lyophilizer

  • Code: M2492509594
  • Status: Visible
  • Condition: Like new
  • Year: 2018
Technical sheet
cisa-m1702077253

Used CISA autoclave

  • Code: M1702077253
  • Status: Visible
  • Condition: Good
  • Year: 1981
Technical sheet
fedegari-fo-3-m1702077481

Used Fedegari FO 3 autoclave

  • Code: M1702077481
  • Status: Visible
  • Condition: Good
  • Year: 1973
Technical sheet
vismara-sterilmat-2280-f-m1702077637

Used Vismara STERILMAT 2280-F sterilizer

  • Code: M1702077637
  • Status: Visible
  • Condition: Good
Technical sheet
used-de-lama-dlst-l-lyophilizer-sterilizer-autoclave-m1902944420

Used De Lama DLST/L sterilizer

  • Code: M1902944420
  • Status: Visible
  • Condition: Good
  • Year: 1998
Technical sheet
de-lama-dlov-m1902944535

Used De Lama DLOV autoclave

  • Code: M1902944535
  • Status: Visible
  • Condition: Good
  • Year: 1998
Technical sheet
de-lama-1-m3-m1903265162

Used De Lama 1 m3 autoclave

  • Code: M1903265162
  • Status: Visible
  • Condition: Good
  • Year: 1992
Technical sheet
hof-m2003707759

Used Hof lyophilizer

  • Code: M2003707759
  • Status: Visible
  • Condition: Good
  • Year: 1991
Technical sheet
fedegari-fof-2-m2003923409

Used Fedegari FOF 2 autoclave

  • Code: M2003923409
  • Status: Visible
  • Condition: Good
  • Year: 1985
Technical sheet
telstar-ffd-randd-m2003998527

Used TELSTAR FFD R&D lyophilizer

  • Code: M2003998527
  • Status: Visible
  • Condition: Like new
  • Year: 2018
Technical sheet
getinge-gec-900-x1450x1350-2-m2104221859

Used Getinge GEC 900 X1450X1350-2 autoclave

  • Code: M2104221859
  • Status: Visible
  • Condition: Good
  • Year: 2007
Technical sheet
getinge-ge-672x920x1350-2-m2104221999

Used Getinge GE 672X920X1350-2 autoclave

  • Code: M2104221999
  • Status: Visible
  • Condition: Good
  • Year: 2006
Technical sheet
icp-ds-100-m2104222231

Used ICP DS 100 sterilizer

  • Code: M2104222231
  • Status: Visible
  • Condition: Good
  • Year: 1996
Technical sheet
used-fedegari-fom3-a-lyophilizer-sterilizer-autoclave-m2104371578

Used Fedegari FOM3/A autoclave

  • Code: M2104371578
  • Status: Visible
  • Condition: Good
  • Year: 2002
Technical sheet
used-fedegari-fod6-1-autoclave-m2104371666

Used Fedegari FOD6/1 autoclave

  • Code: M2104371666
  • Status: Visible
  • Condition: Good
  • Year: 2002
Technical sheet
getinge-gss67h-m2306709796

Used Getinge GSS67H sterilizer

  • Code: M2306709796
  • Status: Visible
  • Condition: Good
  • Year: 2017
Technical sheet
hof-gt-m2407277660

Used Hof GT laboratory freeze dryer

  • Code: M2407277660
  • Status: Visible
  • Condition: Good
Technical sheet
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