Complete line for Bosch vials 24,000 per hour with Isolator since 2009 Consisting of :
1) Filling machine for vials under isolator
2) Depyrogenation oven for Bosch ampoules
3) Vial washing machine with several washing cycles
4)Air treatment unit

1-Filling machine for ampoules under isolator
- Manufacturer: Bosch
- Model : ALF 4080 Year of manufacture : 2009
- Output : 400 ampoules per minute working range
- Diameter : From 9 to 30 mm
- Height : From 60 to 160 mm
- Formats included : 1 - 2ml
- The machine is supplied with ISOLATOR and DEDICATED UTA AND CIP/SIP IPC (vial weighing control).
- The ALF machine series meets all requirements for modern ampoule production. The convincing line concept.
- Extensive experience, state-of-the-art know-how, highly developed engineering and Bosch quality: new dimensions in reliability, economy and flexibility with easy operator control.
- The ALF series has been configured in accordance with pharmaceutical requirements to provide a modern, ergonomic design that offers the customer maximum benefits. Decisive in this design is a basic machine that can be equipped and adapted with various equipment units.

These include:
- Process control system
- Input and output star wheel
- Isolator version

Work and production considerations:
- Easy operator control due to streamlined, uncluttered and well-structured design Easy cleaning.
- All machine functions can be monitored, controlled and operated from a single frontal position.
- Clean room compliance.
- The drive and production segments are clearly separated: full working plane.
- Vials are transferred directly from the sterilisation tunnel to the ALF infeed conveyor.
- Via a sliding conveyor and a transfer wheel, the vials reach the conveyor system that takes them through the work stations: gas washing, filling and sealing.
- Each filling point individually controls the non-contact scanning of the vial necks - 'no vial - no filling'. The vial necks are pre-centred by the pick-up tongs, the vial tips are grasped and introduced into a collection container.
- Post-gasflushing is possible during the sealing procedure. The filled and sealed vials are pushed virtually unloaded into the outlet magazine.

Rotary sliding pumps:
- Bosch offers precision filling for parente- ralisation with its proven rotary sliding pump. Filling without dripping and with maximum precision is guaranteed for a wide range of different properties.
- The gasketless Bosch rotary sliding pumps are equipped with easy vertical cleaning paths. Overhead technology:
- 3 parts: rotary slide valve, pump cylinder, pump piston.
- Without gaskets.
- Easy vertical cleaning paths. ❒
- CIP/SIP capacity.

2) Depyrogenation tank for Bosch vials

Manufacturer : Bosch
Model : HQL 2440S
Year : 2009
Production : 24,000 1 ml vials per hour

HQL systems are ideal for sterilising vials.
This model is exceptional due to the absence of tunnel passages, which is the result of the laminar hot air flow process with its high degree of efficiency.

Sterilisation tunnels are used in the filling lines of the pharmaceutical industry to sterilise glass containers before filling them aseptically.
These tunnels use forced air at temperatures of up to 350 °C.
The Bosch HQL drying and sterilisation tunnels operate with unidirectional flow, with temperature progression process curves and significantly reduced sterilisation times.
They guarantee the constant precision required for validation, qualification and reliable production capacity.
Through a filter, make-up air is introduced into the tunnel.
Inside the tunnel, the air, drawn in by fans, feeds the supply and cooling section through pre-filters and particle filters in separate areas of the tunnel.
Using the laminar flow principle, the air flow is directed vertically into the containers.
Below the conveyor, the air is returned to the fan through a recirculation duct.
The fans need fresh air for the heating section: laminar flow units.
Heating elements in the recirculation duct are used to heat the recirculated air to the preset temperature.
Below the particulate air filters are heating elements that are sent to a temperature recording and control device.
The cooling section operates with laminar flow.
A fan in the cooling section sucks the hot air under the conveyor belt.
The exhaust air volume is adjusted automatically.
The tunnel is equipped with an automatic overpressure control in the cooling section.
Modular system for assembling the tunnel to suit the required power range with optimum energy consumption.
GMP-compliant construction. Compatible container transport systems for stable and non-stable containers.
Safe conveyor belts on the floor and side levels operated simultaneously.
Excellent accessibility and ease of use.
3) Vial washing machine with different washing cycles
(WFI water - sterile air)
Manufacturer : Bosch
Model :RRU 3084 Year of manufacture :2009
Output : 400 ampoules per minute Working range :
Diameter : 9 - 30 mm
Height : 60 - 145 mm
Formats included : 1 -2 ml

The RRU washer and dryer series from Bosch performs ultrasonic cleaning for fast and accurate particulate removal. Its swivel design allows for a small footprint and ease of use, with fast and accurate particulate removal and reliable feeding of small containers.
Bosch RRU rotary heads guarantee excellent results with gentle vial handling. They can be configured for a wide range of formats.
Ideal rotary washer for cleaning vials. It offers optimum accessibility, for example, and is very easy to use. Ranges and treatment capacities depend on individual containers, line integration, etc. GMP-compliant construction; small size; safe container transport; high level of ultrasonic cleaning; stations for internal and external container washing; with pump station; quick format change.